MOTS-C 40mg Research Peptide – Advanced Metabolic Research Compound

Unlock advanced cellular insights with MOTS-C 40mg, a premium, high-concentration formulation designed exclusively for laboratory testing and in vitro or in vivo preclinical research models. MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a groundbreaking 16-amino acid peptide naturally encoded within the mitochondrial genome. Functioning as a “mitokine” or mitochondrial hormone, this unique compound plays an integral role in signaling between the mitochondria and the nucleus to regulate systemic metabolism and cellular homeostasis under stress conditions.

The 40mg high-capacity vial offers an optimal quantity for complex, multi-stage, or long-term comparative evaluation cycles without requiring frequent reconstitution protocols.

MOTS-C 40mg Core Areas of Scientific Research

Metabolic Regulation & AMPK Activation: Research indicates that MOTS-C intercepts the cellular folate cycle to promote the accumulation of the endogenous AMP analog AICAR. This shift triggers AMPK (AMP-activated protein kinase), a master metabolic regulatory switch that modulates cellular glucose uptake, fat oxidation, and insulin sensitivity profiles.

Exercise Mimetic Analysis: Studies explore MOTS-C as an exercise mimetic. In animal models, systemic administration has demonstrated a profound capacity to enhance overall physical endurance, grip strength, and gait adaptability.

Cellular Longevity & Anti-Aging Phenotypes: Because naturally occurring MOTS-C levels steadily decline with age, researchers utilize this peptide to evaluate its potential to reverse age-related muscle atrophy, support bone mineral density, and counter diet-induced metabolic dysfunction.

Mitohormesis & Oxidative Stress Support: Under metabolic or oxidative stress, MOTS-C translocates directly to the nucleus. It binds with transcription factors like NRF2 to upregulate adaptive, cytoprotective, and antioxidant response genes.